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Female sexual dysfunctions (such as anorgasmia,
hypoactive sexual desire, sexual aversion, sexual
arousal disorders, and sexual pain disorders, as vaginis-
mus) may also be related to acquired PE.
PE exerts a significant psychological burden on men,
their partners, the male/partner relationship, and their
overall relationship. Men with PE show other negative
effects, including a general negative affect associated
with sexual situations, and more intense feelings of
embarrassment/guilt, worry/tension and fear of failure.
Psychotherapy and behavioral interventions improve
ejaculatory control by helping men/ couples to: learn
techniques to control and/or delay ejaculation; gain
confidence in their sexual performance; lessen
performance anxiety; modify rigid sexual repertoires;
surmount barriers to intimacy; resolve interper-sonal
issues that precipitate and maintain the dysfunction;
increase communication and come to terms with
feelings/thoughts that interfere with sexual function.
The use of anesthetics to diminish the sensitivity of the
glans penis is probably the oldest known form of
treating PE.
On-demand administration of Dapoxetine has received
regulatory approval as an on-demand treatment for PE
in several parts of the world.
Definitions of premature ejaculation (PE) is
characterized by : an ejaculation that always or nearly
always occurs prior to or within about 1 minute of
vaginal penetration, an inability to delay ejaculation on
all or nearly all vaginal penetrations, and with negative
personal consequences, such as distress, bother,
frustration, and/or the avoidance of sexual intimacy.
The population of men with PE is not homogenous and
includes lifelong PE, acquired PE, natural variable.
Various epidemiological studies have shown that about
20–30% of men have complaints of premature
ejaculation.
Ejaculatory latency time in life long PE is probably a
biological variable, which is genetically determined and
may differ between populations and cultures, ranging
from extremely rapid through average to slow
ejaculation.
Acquired PE can often be traced to either
neurobiogenic (endocrine, urologic, neurobiologic) or
psychogenic factors, or in some instances, both.
PE co-exists in about one-third of patients complaining
of erectile dysfunction.
Hypoactive sexual desire may lead to PE, due to an
unconscious desire to abbreviate unwanted
penetration.
Definition, Epidemiology, and Pathophysiology