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5

disease increases with age. This condition is most

commonly acquired at about age 55. A man can be born

with a curved penis, but this is not Peyronies disease

but usually a penile curvature.

The actual occurrence of Peyronie’s disease may be

higher due to men’s embarrassment and health care

providers’ limited reporting.1 The disease is rare in

young men, although it has been reported in men in

their 30s.1 The chance of developing Peyronie’s

Who gets Peyronie's disease?

Autoimmune disorders associated with Peyronie’s

disease include

systemic lupus erythematosus

- inflammation and

damage to various body tissues, including the joints,

skin, kidneys, heart, lungs, blood vessels, and brain

Sjögren’s syndrome

- inflammation and damage to

the glands that make tears and saliva

Behcet’s syndrome

- inflammation of the blood

vessels

Family History of Peyronie’s Disease

Medical experts believe that Peyronie’s disease may run

in some families. For example, a man whose father or

brother has Peyronie’s disease may have an increased

chance of getting the disease.

Aging

The chance of getting Peyronie’s disease increases with

age. Age-related changes in the elasticity of tissues in

the penis may cause it to be more easily injured and

The following factors may increase a man’s chance of

developing Peyronie’s disease:

vigorous sexual or nonsexual activities that cause

microscopic injury to the penis

certain connective tissue and autoimmune disorders

a family history of Peyronie’s disease

aging

vigorous Sexual and Nonsexual Activities

men whose sexual or nonsexual activities cause

microscopic injury to the penis are more likely to

develop Peyronie’s disease.

Connective Tissue and Autoimmune Disorders

Men who have certain connective tissue and

autoimmune disorders may have a higher chance of

developing Peyronie’s disease. A common example is a

condition known as Dupuytren’s disease, an abnormal

cordlike thickening across the palm of the hand.

Dupuytren’s disease is also known as Dupuytren’s

contracture. Although Dupuytren’s disease is fairly

common in older men, only about 15 percent of men

with Peyronie’s disease will also have Dupuytren’s

disease. Other connective tissue disorders associated

with Peyronie’s disease include:

Plantar fasciitis

- inflammation of the plantar fascia,

thick tissue on the bottom of the foot that connects

the heel bone to the toes and creates the arch of the

foot

Scleroderma

- abnormal growth of connective

tissue, causing it to get thick and hard; scleroderma

can cause swelling or pain in muscles and joints

Who is more likely to develop Peyronie’s disease?